science

NAD⁺ restores memory in Alzheimer’s disease models by correcting RNA errors

Alzheimer’s disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease. In AD, a major contributor to neuronal dysfunction is the protein tau. An international team of researchers has reported a new mechanism by which boosting the natural metabolite NAD⁺ can protect the brain from the degeneration associated with AD. NAD⁺ (nicotinamide adenine dinucleotide, oxidized form) is a vital metabolite involved in energy metabolism and neuronal resilience in the body. It normally declines with.

healthmusicscience

Listening To Music Linked To 39% Lower Dementia Risk, New Study Says

The post Listening To Music Linked To 39% Lower Dementia Risk, New Study Says appeared com. A new study showed that regularly listening to music, whether its’ from Sir Mix A Lot (pictured here) or someone else, is associated with lower likelihoods of cognitive decline and dementia. That’s because fellas (yeah,) fellas (yeah) and ladies (yeah), ladies (yeah) a new analysis recently published in the International Journal of Geriatric Psychiatry found that those over 70 years of age who always listened to music had a 39% lower risk of having dementia than those who never, rarely or only sometimes did. And playas, meaning those who played a musical instrument, had a 35% lower risk of having dementia than those who didn’t. Both Listening To And Playing Music Were Associated With Lower Likelihoods of Dementia The analysis was conducted by a research team from Monash University in Melbourne, Australia, (Emma Jaffa, Zimu Wu, Alice Owen, Aung Azw Zaw Phyo, Robyn L. Woods, Suzanne G. Orchard, Trevor T.-J. Chong and Joanne Ryan) and Rush University (Raj C. Shah) and Hennepin Health (Anne Murray) in the U. S. The team looked at data on 10, 893 older Australians from the ASPirin in Reducing Events in the Elderly (ASPREE) study and the ASPREE Longitudinal Study of Older Persons (ALSOP) sub‐study. While this study didn’t ask participants specifically about whether they listed to that Sir Mix-a-Lot song, it did inquire about their music listening and playing habits in general. Here are some other results that weren’t necessarily newly radical. Those with the music in them-meaning they were always listeining to music-had a 17% lower rate of cognitive impairment, along with better scores in overall cognition and the ability to recall everyday.

science

How an obesity gene may prevent heart disease

Obesity is often linked to serious health problems like heart disease and high cholesterol. But a new study has found something surprising: people who are obese due to a rare genetic condition might actually have better heart health than expected. The research, published in Nature Medicine, focused on people with a specific gene mutation called [.] The post How an obesity gene may prevent heart disease appeared first on Knowridge Science Report.